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CHIEF-PD Trial Manager

  • University of Bristol
  • Bristol
  • 11/01/2019
Full time

Job Description


We are seeking a talented individual to act as the Trial Manager for the CHIEF-PD clinical trial - Choinesterase inhibitors to prevent falls in Parkinson's disease. This post offers an excellent opportunity for an experienced research leader to join a multidisciplinary team within the University of Bristol, and collaborators at participating NHS hospitals.

CHIEF-PD is an NIHR-HTA funded placebo controlled randomised controlled trial which examines whether rivastigmine (a dementia drug) can prevent people with Parkinson's from falling. The trial is structured with an internal pilot phase and a formal review at 18 months to determine if the trial will proceed with a planned total of 51 months (including analysis and dissemination) in 26 centres.

Based within the Bristol Randomised Trials Collaboration (BRTC), a UKCRC-registered trials unit, you will be accountable for making sure that the trial is conducted to the highest possible standards and complies with all regulatory requirements and good clinical practice. The task of the Trial Manager is to lead all aspects of the trial and to liaise with the PIs, collaborators, trial management committees and centre staff to oversee set up, and to ensure recruitment and follow-up targets are achieved within the proposed time frame in a properly conducted trial.

You will have substantial experience in research, experience of successful trial management (preferably multi-centre) and the proven ability to apply leadership. Good communication skills are required as you will be working within the NHS and the University, liaising with research staff, clinicians and collaborating academics. In addition, you will prepare update reports for the management team and funders, and be expected to play a major part in disseminating findings, presenting at conferences and contributing substantially to publications. The post provides the opportunity for autonomy and freedom to act independently with organisational policies, and will require excellent interpersonal and negotiating skills. You will be able to demonstrate an ability to organise and motivate others, and to take a high level of responsibility.

Name and email for informal contact: Dr Emily Henderson, [email protected]

We appreciate and value difference, seeking to attract, develop and retain a diverse mix of talented people that will contribute to the overall success of Bristol and help maintain our position as one of the world's leading universities.